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Immunology and Infection

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Analysis of Iophenoxic Acid Analogues in Small Indian Mongoose (Herpestes Auropunctatus) Sera for Use as an Oral Rabies Vaccination Biological Marker

Article DOI: 10.3791/59373-v • 11:28 min • May 31st, 2019
May 31st, 2019 •
1, 1, 1, 1, 1, 2, 2, 1
1US Department of Agriculture, Animal and Plant Health Inspection Service, Wildlife Services, National Wildlife Research Center, 2IDT Biologika GmbH, Am Pharmapark

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Summary
Automatic Translation

We offered captive mongooses placebo oral rabies vaccine baits with ethyl or methyl iophenoxic acid as a biomarker and verified bait uptake using a novel liquid chromatography with tandem mass spectrometry (LC-MS/MS) method.

Tags

Iophenoxic Acid Biological Marker Mongoose Serum Quantification Protein Precipitation Technique Mobile Phase A Mobile Phase B Diluent Methyl-IPA Mass Measurement Acetonitrile Stock Preparation
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