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Journal / Biochemistry / Nükliosomal Histones in vitro Ubiquitination ve…
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Biochemistry

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JoVE Journal Biochemistry
Nükliosomal Histones in vitro Ubiquitination ve Deubiquitination bulguları
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Nükliosomal Histones in vitro Ubiquitination ve Deubiquitination bulguları

Article DOI: 10.3791/59385-v • 11:36 min • July 25th, 2019
July 25th, 2019 •
*1, *1, 1, 1, 1, 1, 1, 1,2, 1,2
1Maisonneuve-Rosemont Hospital Research Center and Department of Medicine, University of Montréal, 2Lunenfeld-Tanenbaum Research Institute, Sinai Health System
* These authors contributed equally

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Ubiquitination hücresel süreçlerde önemli roller oynar ve sıkıca deubiquitination tarafından koordine edilen bir post-translational modifikasyon olduğunu. Her iki reaksiyon kusurları insan patolojileri altında yatan. Biz arıtılmış bileşenleri kullanarak in vitro mayası ve deubiquitination reaksiyonu yürütmek için protokoller sunuyoruz.

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Biyokimya sayı 149 ubiquitination deubiquitination E3 Ubiquitin ligaz PRC1 deubiquitinase PR-DUB kromatin BAP1 ASXL BMI1 RING1B H2A
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