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Journal / Immunology and Infection / 脓毒症诱导免疫抑制的切卡结扎和穿刺和鼻内感染双重模型的设计…
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Immunology and Infection
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JoVE Journal Immunology and Infection
脓毒症诱导免疫抑制的切卡结扎和穿刺和鼻内感染双重模型的设计
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脓毒症诱导免疫抑制的切卡结扎和穿刺和鼻内感染双重模型的设计

Article DOI: 10.3791/59386-v • 07:30 min • June 15th, 2019
June 15th, 2019 •
*1,2, *1,2, *2,3, 1, 3, 2
1West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, 2Department of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, 3State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Surgery Research, Daping Hospital, Army Medical University
* These authors contributed equally

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该协议描述了在免疫抑制条件下测量继发医院感染的传染性结果的技术,首先通过建立结扎/穿刺小鼠,然后挑战他们与鼻内感染创建一个临床相关的免疫抑制败血症模型。

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免疫学和感染 问题 148 冠状结扎和穿刺 鼻内感染 败血症诱导免疫抑制 免疫抑制败血症 败血症,金黄色葡萄球菌 鼻膜肺炎 小鼠 双模型 双击模型
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