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Journal / Bioengineering / Hiperpolarize Spin-Kafes Gevşeme manyetik alan…
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Bioengineering

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JoVE Journal Bioengineering
Hiperpolarize Spin-Kafes Gevşeme manyetik alan bağımlılığının ölçülmesi [1-13C]pirüuvat
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Hiperpolarize Spin-Kafes Gevşeme manyetik alan bağımlılığının ölçülmesi [1-13C]pirüuvat

Article DOI: 10.3791/59399-v • 11:57 min • September 13th, 2019
September 13th, 2019 •
1, 2, 1,2,3
1Department of Medical Biophysics, Western University, 2Imaging Research Laboratory, Robarts Research Institute, Western University, 3Ontario Institute for Cancer Research

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Hızlı alan döngüsü netometrisi kullanarak, dinamik nükleer polarizasyon yoluyla hiperpolarize edilmiş 13C'lik zenginleştirilmiş bileşiklerin spin-kafes gevşeme süresinin manyetik alan bağımlılığını ölçmek için bir protokol sayılmaktadır. Özellikle, bunu[1-13C] pirüuvat ile gösterdik, ancak protokol diğer hiperpolarize substratlara genişletilebilir.

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Biyomühendislik Sayı 151 pirüvat spin-kafes gevşeme dinamik nükleer polarizasyon alan-bisiklet relaxometrisi nükleer manyetik gevşeme dağılımı (NMRD) hiperpoloarizasyon
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