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Journal / Biochemistry / 用于筛查绝经后心血管功能障碍的外源雌激素治疗的活体雌激素缺乏小鼠模型…
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Biochemistry

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JoVE Journal Biochemistry
用于筛查绝经后心血管功能障碍的外源雌激素治疗的活体雌激素缺乏小鼠模型
Capturing Actively Produced Microbial Volatile Organic Compounds from Human-Associated Samples with Vacuum-Assisted Sorbent Extraction
Journal (Biochemistry)
Capturing Actively Produced Microbial Volatile Organic Compounds from Human-Associated Samples with Vacuum-Assisted Sorbent Extraction
Electrochemical Detection of Deuterium Kinetic Isotope Effect on Extracellular Electron Transport in Shewanella oneidensis MR-1
Journal (Biochemistry)
Electrochemical Detection of Deuterium Kinetic Isotope Effect on Extracellular Electron Transport in Shewanella oneidensis MR-1
 
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用于筛查绝经后心血管功能障碍的外源雌激素治疗的活体雌激素缺乏小鼠模型

Article DOI: 10.3791/59536-v • 06:27 min • August 13th, 2019
August 13th, 2019 •
1, 2, 1
1Institute of Medicinal Plant Development (IMPLAD), Chinese Academy of Medical Sciences & Peking Union Medical College, 2Shandong University of Traditional Chinese Medicine

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临床上,更年期妇女雌激素缺乏可能加重脂质紊乱和动脉粥样硬化的发生率。我们通过在apoE-/-小鼠的双背侧切口,通过双边卵巢切除术建立了体内雌激素缺乏模型。小鼠模型适用于绝经后心血管功能障碍的外源雌激素治疗。

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生物化学 问题 150 卵巢切除术 动脉粥样硬化 双背侧切口 过侧给药 内膜培养素厚度 超声心动图
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