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JoVE Journal Neuroscience
Målretting Alpha Synuclein aggregater i hud perifere nerve fibre av fri-flytende Immunofluorescence analysen
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Målretting Alpha Synuclein aggregater i hud perifere nerve fibre av fri-flytende Immunofluorescence analysen

Article DOI: 10.3791/59558-v • 08:33 min • June 25th, 2019
June 25th, 2019 •
1, 1, 1,2,3,4, 1,2
1Laboratory for Biomedical Neurosciences, Neurocenter of Southern Switzerland, 2Neurology Department, Neurocenter of Southern Switzerland, 3Department of Neurology, Inselspital, Bern University Hospital, University of Bern, 4Faculty of Biomedical Sciences, Università della Svizzera Italiana

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Her presenterer vi en protokoll for en frittflytende indirekte immunofluorescence analysen på huden biopsi seksjoner som gjør det mulig for identifisering av sykdom spesifikke konformasjon varianter av Alpha synuclein involvert i Parkinsons sykdom og flere proteiner av perifere nervesystemet.

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Nevrovitenskap hud biopsi perifere nervesystemet indirekte immunofluorescence frittflytende protein genet produkt 9,5 Alpha Synuclein fosforylert Alpha Synuclein 5G4 protein aggregater
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