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Journal / Neuroscience / Transplantasjon av Chemogenetically utviklet…
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Neuroscience

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JoVE Journal Neuroscience
Transplantasjon av Chemogenetically utviklet kortikale Interneuron forfedre inn tidlig postnatal Mouse hjerner
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Transplantasjon av Chemogenetically utviklet kortikale Interneuron forfedre inn tidlig postnatal Mouse hjerner

Article DOI: 10.3791/59568-v • 06:09 min • August 26th, 2019
August 26th, 2019 •
1,2, 3, 3, 1
1Nervous System Development and Homeostasis Laboratory, The Francis Crick Institute, 2Neuroscience Centre, Biomedical Sciences Research Centre "Al. Fleming", 3Centre for Developmental Neurobiology, King's College London

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Her presenterer vi en protokoll, designet for å bruke chemogenetic verktøy for å manipulere aktiviteten til kortikale interneuron forfedre transplantert inn i cortex av tidlige postnatal mus.

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Nevrovitenskap kortikale interneurons ganglionic dominans hjerne skive electroporation intrakraniell injeksjoner designer reseptorer utelukkende aktiveres av designer narkotika (DREADD)
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