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Journal / Behavior / Paw-Print Analysis of Contrast-Enhanced…
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Behavior

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JoVE Journal Behavior
Paw-Print Analysis of Contrast-Enhanced Recordings (PrAnCER)
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Paw-Print Analysis of Contrast-Enhanced Recordings (PrAnCER): A Low-Cost, Open-Access Automated Gait Analysis System for Assessing Motor Deficits

Article DOI: 10.3791/59596-v • 06:25 min • August 12th, 2019
August 12th, 2019 •
1, 1, 3, 1,2
1Cognitive, Linguistic & Psychological Sciences, Brown University, 2Department of Neuroscience, Brown University, 3Department of Neurosurgery, Warren Alpert Medical School, Brown University

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We describe a novel gait analysis system, Paw-Print Analysis of Contrast-Enhanced Recordings (PrAnCER), an open-access automated system for the quantification of gait characteristics in rats that utilizes a novel semitransparent floor to automatically quantify gait. This system was validated using the haloperidol model of Parkinson’s Disease.

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Gait Analysis System PrAnCER Motor Deficits Paw-print Analysis Contrast-enhanced Recordings Low-cost Open-access Automated User-friendly Affordable Accurate Commercial Gait Systems Semitransparent Floor High Contrast Paw Prints Motor Function Assessment Injury And Disease Models Spinal Cord Damage Nerve Damage Neurodegenerative Diseases Neuromuscular Disorders Gait Apparatus Animal Models Clear Plexiglass Enclosed Walkway 16-pound Drafting Vellum Camera With At Least 30 Frames Per Second Frame Rate 12-volt Light Emitting Diode Lights Habituation Of Animals
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