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A Human Peripheral Blood Mononuclear Cell (PBMC) Engrafted Humanized Xenograft Model for Translational Immuno-oncology (I-O) Research

Article DOI: 10.3791/59679-v • 08:17 min • August 15th, 2019
August 15th, 2019 •
*1, *1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1
1BeiGene (Beijing) Co., Ltd.
* These authors contributed equally

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Wir beschreiben eine menschliche periphere Mononuklezelle (PBMC) – basierendes humanisiertes Xenograft-Mausmodell für translationale Immunonkologieforschung. Dieses Protokoll könnte als allgemeine Leitlinie für die Erstellung und Charakterisierung ähnlicher Modelle für die Bewertung von I-O-Therapien dienen.

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Retraktion Ausgabe 150 Immunonkologie (I-O) periphere mononukleäre Blutzelle (PBMC) Tislelizumab BGB-A317 immundefiziös humanisiert Cyclophosphamid (CP) patientenabgeleitetes Xenograft (PDX)
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