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JoVE Journal Cancer Research
Et humant perifert blod mononukleære Cell (PBMC) Engrafted Humanisert Xenograft modell for translational Immuno-onkologi (I-O) forskning
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Et humant perifert blod mononukleære Cell (PBMC) Engrafted Humanisert Xenograft modell for translational Immuno-onkologi (I-O) forskning

Article DOI: 10.3791/59679-v • 08:17 min • August 15th, 2019
August 15th, 2019 •
*1, *1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1
1BeiGene (Beijing) Co., Ltd.
* These authors contributed equally

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Vi beskriver en menneskelig perifere blod mononukleære celle (PBMC)-basert humanisert xenograft mus modell for translational Immuno-onkologi forskning. Denne protokollen kan tjene som en generell retningslinje for etablering og karakteriserer av lignende modeller for I-O terapi vurdering.

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Tilbaketrekking Immuno-onkologi (I-O) perifert blod mononukleære celle (PBMC) Tislelizumab BGB-A317 immunodeficient humanisert cyklofosfamid (CP) pasient-avledet xenograft (PDX)
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