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Journal / Bioengineering / Human neurale Organoide zur Untersuchung von…
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Bioengineering

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JoVE Journal Bioengineering
Human neurale Organoide zur Untersuchung von Hirntumor und neurodegenerativen Erkrankungen
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Human neurale Organoide zur Untersuchung von Hirntumor und neurodegenerativen Erkrankungen

Article DOI: 10.3791/59682-v • 09:36 min • June 28th, 2019
June 28th, 2019 •
*1, *2, 2, 3, 3, 4, 5, 4, 2
1Laboratory of Tumor Immunology, Translational Research Center in Onco-Hematology, Department of Internal Medicine Specialties, Faculty of Medicine, University of Geneva, 2Department of Pathology and Immunology, University Medical Center, University of Geneva, 3Laboratory of Toxicology and Therapeutic Drug Monitoring, Geneva University Hospitals, 4Tissue Engineering Laboratory, Hepia/HES-SO, University of Applied Sciences Western Switzerland, 5Laboratory of Experimental cell therapy, Department of Diagnostics, Geneva University Hospitals
* These authors contributed equally

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Diese Studie stellt Protokolle vor und beschreibt Protokolle, um zwei spezifische menschliche neurale Organoide als relevantes und genaues Modell für die Untersuchung von 1) der Entwicklung des menschlichen Glioblastoms innerhalb menschlicher neuronaler Organoide ausschließlich beim Menschen und 2) neuronendopaminergen Organoiden abzuleiten. Differenzierung, die ein dreidimensionales Organoid erzeugt.

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Bioengineering Ausgabe 148 neurales Organoid Glioblastom multiforme Krebsstammzellen menschliche embryonale Stammzellen dopaminerge Neuronen neurodegenerative Erkrankungen
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