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Journal / Medicine / Kontinuerlig blodprøvetagning i små dyr Positron…
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Medicine

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JoVE Journal Medicine
Kontinuerlig blodprøvetagning i små dyr Positron emission Tomography/computertomografi gør det muligt at måle den arterielle indgangsfunktion
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Kontinuerlig blodprøvetagning i små dyr Positron emission Tomography/computertomografi gør det muligt at måle den arterielle indgangsfunktion

Article DOI: 10.3791/59701-v • 10:21 min • August 8th, 2019
August 8th, 2019 •
1, 2, 3, 3, 4, 2, 1, *3, *3
1Institute of Anatomy, Rostock University Medical Center, 2Department of Nuclear Medicine, Rostock University Medical Center, 3Core Facility Multimodal Small Animal Imaging, Rostock University Medical Center, 4Rudolf-Zenker-Institute for Experimental Surgery, Rostock University Medical Center
* These authors contributed equally

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Her beskrives en protokol til kontinuerlig blodprøvetagning under PET/CT-scanning af rotter til måling af den arterielle indgangsfunktion (AIF). Kateteriseringen, kalibrering og opsætning af systemet og dataanalyse af blodets radioaktivitet er påvist. De genererede data giver inputparametre for efterfølgende bio-Kinetic modellering.

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Medicin PET Imaging kinetiske modellering kvantificering radiotracer optagelse kontinuerlig blodprøvetagning arteriel kanyle arteriovenøs shunt arteriel indgangsfunktion lille dyr gnaver rotte
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