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Journal / Neuroscience / Generering av Alpha-Synuclein preformed fibrils…
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Neuroscience

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JoVE Journal Neuroscience
Generering av Alpha-Synuclein preformed fibrils fra monomerer og bruk in vivo
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Generering av Alpha-Synuclein preformed fibrils fra monomerer og bruk in vivo

Article DOI: 10.3791/59758-v • 09:44 min • June 2nd, 2019
June 2nd, 2019 •
1, 2, 1,3, 1, 4, 5, 1, 1,3,6
1Department of Translational Science and Molecular Medicine, Michigan State University, 2The Michael J. Fox Foundation for Parkinson's Research, 3Neuroscience Program, Michigan State University, 4Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, 5Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, 6Mercy Health Hauenstein Neuroscience Medical Center

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Målet med denne artikkelen er å skissere trinnene som kreves for generering av fibrils fra monomere Alpha-synuclein, påfølgende kvalitetskontroll, og bruk av preformed fibrils in vivo.

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Nevrovitenskap Alpha-Synuclein monomerer preformed fibrils Parkinsons sykdom kvalitetskontroll Stereotaxic Surgery
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