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JoVE Journal Chemistry
Enzymatische synthese van Epoxidized metabolieten van docosahexaeenzuur, Eicosapentaeenzuur en arachidonzuur zuren
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Enzymatische synthese van Epoxidized metabolieten van docosahexaeenzuur, Eicosapentaeenzuur en arachidonzuur zuren

Article DOI: 10.3791/59770-v • 13:05 min • June 28th, 2019
June 28th, 2019 •
1, 1, 1, 1
1Department of Pharmacology and Toxicology, Michigan State University

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Wij presenteren een methode nuttig voor grootschalige enzymatische synthese en zuivering van specifieke enantiomeren en regioisomers van epoxiden van arachidonzuur zuur (AA), docosahexaeenzuur zuur (DHA), en Eicosapentaeenzuur zuur (EPA) met het gebruik van een bacteriële cytochroom P450 enzym (BM3).

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Chemie epoxy meervoudig onverzadigde vetzuren lipiden enzymatische synthese enantioselectieve synthese Omega-3 vetzuren eicosanoïden
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