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Biochemistry

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JoVE Journal Biochemistry
En dubbel humaniserad BLT-möss modell med en stabil människa-liknande Gut Microbiome och människans immun system
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En dubbel humaniserad BLT-möss modell med en stabil människa-liknande Gut Microbiome och människans immun system

Article DOI: 10.3791/59773-v • 07:32 min • August 30th, 2019
August 30th, 2019 •
1,2, 1,2, 3, 1,2
1Nebraska Center for Virology, 2School of Biological Sciences, University of Nebraska-Lincoln, 3Department of Food Science and Technology, University of Nebraska-Lincoln

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Vi beskriver en ny metod för att generera dubbla humaniserade BLT-möss som har ett funktionellt humant immunförsvar och en stabil inympad människoliknande Gut microbiome. Detta protokoll kan följas utan behov av bakteriefria möss eller gnotobiotiska anläggningar.

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Biokemi dubbel humaniserad BLT-möss Gut microbiome immunitet antibiotika fekal transplantation
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