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Biochemistry

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JoVE Journal Biochemistry
En dobbelt humaniseret BLT-mus model med en stabil menneskelig-lignende Gut Mikrobiom og humant immun system
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Journal (Biochemistry)
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Journal (Biochemistry)
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En dobbelt humaniseret BLT-mus model med en stabil menneskelig-lignende Gut Mikrobiom og humant immun system

Article DOI: 10.3791/59773-v • 07:32 min • August 30th, 2019
August 30th, 2019 •
1,2, 1,2, 3, 1,2
1Nebraska Center for Virology, 2School of Biological Sciences, University of Nebraska-Lincoln, 3Department of Food Science and Technology, University of Nebraska-Lincoln

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Vi beskriver en ny metode til generering af dobbelte humaniserede BLT-mus, der har et funktionelt humant immunsystem og et stabilt menneskelignende tarm mikrobiom. Denne protokol kan følges uden behov for kimfri mus eller gnotobiotiske faciliteter.

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Biokemi dobbelt humaniseret BLT-mus Gut mikrobiome immunitet antibiotika fækal transplantation
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