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JoVE Journal Behavior
Sammenlignende læsioner analyse gennem en målrettet sekvensering tilgang
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Sammenlignende læsioner analyse gennem en målrettet sekvensering tilgang

Article DOI: 10.3791/59844-v • 08:16 min • November 5th, 2019
November 5th, 2019 •
1, 1, 2, 3, 2, 1, 1, 1,2, 1,2
1ARC-Net Research Centre, University and Hospital Trust of Verona, 2Department of Diagnostics and Public Health, Section of Pathology, University and Hospital Trust of Verona, 3Department of Medicine (DIMED), Surgical Pathology and Cytopathology Unit, University of Padua

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Denne artikel beskriver en metode til at identificere klonale og subklonale ændringer blandt forskellige prøver fra en given patient. Selv om de eksperimenter, der er beskrevet her fokusere på en bestemt tumortype, tilgangen er stort set gælder for andre solide tumorer.

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Adfærd problem 153 intra-tumor heterogenitet metastaser biomarkører klonal målrettet sekvensering immun histokemi "driver" ændringer subklonal
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