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Presynapse vorming assay met Presynapse Organizer kralen en "neuron Ball" cultuur
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Presynapse vorming assay met Presynapse Organizer kralen en "neuron Ball" cultuur

Article DOI: 10.3791/59893-v • 10:17 min • August 2nd, 2019
August 2nd, 2019 •
1, 1, 1
1Functional Structure Biology Laboratory, Department of Medical Life Science, Yokohama City University Graduate School of Medical Life Science

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Presynapse vorming is een dynamisch proces, met inbegrip van accumulatie van synaptische eiwitten in de juiste volgorde. Bij deze methode wordt presynapse vorming geactiveerd door kralen geconjugeerd met een presynapse Organizer eiwit op axonale vellen van "neuron Ball" cultuur, zodat accumulatie van synaptische eiwitten gemakkelijk kan worden geanalyseerd tijdens presynapse vorming.

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Neurowetenschappen uitgave 150 presynapse LRRTM2 lokale vertaling fragiel X-syndroom FMRP Munc18-1 actieve zone excitatory Synapse
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