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Murine appendectomy model af kronisk colitis associeret kolorektal cancer ved præcis lokalisering af Caecal patch
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Murine appendectomy model af kronisk colitis associeret kolorektal cancer ved præcis lokalisering af Caecal patch

Article DOI: 10.3791/59921-v • 08:51 min • August 24th, 2019
August 24th, 2019 •
1, 2,3, 1, 2,3, 1, 4, 1,5, 1,6, 1,2, 1
1Department of General Surgery, The First Affiliated Hospital, Xi'an Jiaotong University, 2Institute of Medical Research, Northwestern Polytechnical University, 3School of Life Sciences, Northwestern Polytechnical University, 4Department of Medicine, Xi'an Jiaotong University, 5Princess Margaret Cancer Center, University of Health Network, 6Department of Pathology, Nanjing Medical University

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Den præsenterede protokol beskriver en facile kirurgisk fjernelse af tillægget (caecal patch) i en mus efterfulgt af induktion af inflammatorisk tarmsygdom-associeret kolorektal cancer. Denne murine appendectomy model muliggør undersøgelse af den biologiske rolle af tillægget i patogenesen af menneskelig gastrointestinal sygdom.

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Medicin murine model appendiks caecalis relativt patch gastrointestinal anatomi tyktarm tumor IgA azoxymethane dextran sulfat natrium IBD
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