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Murine Appendectomy Modello di Cronica Colite Associata Cancro Colorettale da Localizzazione precisa di Patch Caecal

Article DOI: 10.3791/59921-v • 08:51 min • August 24th, 2019
August 24th, 2019 •
1, 2,3, 1, 2,3, 1, 4, 1,5, 1,6, 1,2, 1
1Department of General Surgery, The First Affiliated Hospital, Xi'an Jiaotong University, 2Institute of Medical Research, Northwestern Polytechnical University, 3School of Life Sciences, Northwestern Polytechnical University, 4Department of Medicine, Xi'an Jiaotong University, 5Princess Margaret Cancer Center, University of Health Network, 6Department of Pathology, Nanjing Medical University

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Il protocollo presentato descrive una facile rimozione chirurgica dell'appendice (patch caecale) in un topo seguita dall'induzione del cancro colorettale associato alla malattia intestinale infiammatoria. Questo modello di appendicosa murina consente lo studio del ruolo biologico dell'appendice nella patogenesi della malattia gastrointestinale umana.

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Medicina Numero 150 modello murino appendice cerotto cecese anatomia gastrointestinale intestino crasso tumore IgA azoxymetano sodio di solfato dextran IBD
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