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Murine Appendektomi modell av kronisk kolitt assosiert tykktarmskreft ved presis lokalisering av Caecal patch
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Murine Appendektomi modell av kronisk kolitt assosiert tykktarmskreft ved presis lokalisering av Caecal patch

Article DOI: 10.3791/59921-v • 08:51 min • August 24th, 2019
August 24th, 2019 •
1, 2,3, 1, 2,3, 1, 4, 1,5, 1,6, 1,2, 1
1Department of General Surgery, The First Affiliated Hospital, Xi'an Jiaotong University, 2Institute of Medical Research, Northwestern Polytechnical University, 3School of Life Sciences, Northwestern Polytechnical University, 4Department of Medicine, Xi'an Jiaotong University, 5Princess Margaret Cancer Center, University of Health Network, 6Department of Pathology, Nanjing Medical University

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Den presenterte protokollen beskriver en facile kirurgisk fjerning av vedlegget (caecal patch) i en mus etterfulgt av induksjon av inflammatorisk tarmsykdom-assosiert tykktarmskreft. Denne murine appendektomi modellen muliggjør gransking av den biologiske rollen til tillegget i patogenesen av menneskelig gastrointestinal sykdom.

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Medisin murine modell vedlegg caecal patch Gastrointestinal anatomi stor tarm tumor IgA azoxymethane dextran sulfat natrium IBD
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