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Journal / Developmental Biology / 면역 결핍 마우스에서 인간 골격 근 이종이식…
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Developmental Biology

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JoVE Journal Developmental Biology
면역 결핍 마우스에서 인간 골격 근 이종이식 수행
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면역 결핍 마우스에서 인간 골격 근 이종이식 수행

Article DOI: 10.3791/59966-v • 07:48 min • September 16th, 2019
September 16th, 2019 •
1,2, 2,3, 1,2,3,4, 1,2,4
1Graduate Program in Cellular and Molecular Medicine, Johns Hopkins University School of Medicine, 2Department of Neurology, Johns Hopkins University School of Medicine, 3Kennedy Krieger Institute, 4Department of Neuroscience, Johns Hopkins University School of Medicine

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복잡한 인간 질병은 전통적인 실험실 모형 시스템에서 모델링하는 것이 어려울 수 있습니다. 여기에서, 우리는 면역 결핍 마우스로 인간 골격 근 생검의 이식을 통해 인간 근육 질병을 모델링하는 외과 접근을 기술합니다.

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발달 생물학 문제 151 이종이식 골격 근 이식 모델 NOD-Rag1nullIL2r γnull 마우스 면역 손상 근염 근육 질환
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