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Quantitative Approaches for Studying Cellular Structures and Organelle Morphology in Caenorhabditis elegans
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Quantitative Approaches for Studying Cellular Structures and Organelle Morphology in Caenorhabditis elegans

Article DOI: 10.3791/59978-v • 08:47 min • July 5th, 2019
July 5th, 2019 •
*1, *1, *1, 1
1Neuroscience Program, Monash Biomedicine Discovery Institute and Department of Anatomy and Developmental Biology, Monash University, Melbourne VIC 3800, Australia.
* These authors contributed equally

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Summary
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This study outlines quantitative measurements of synaptic size and localization, muscle morphology, and mitochondrial shape in C. elegans using freely available image processing tools. This approach allows future studies in C. elegans to quantitatively compare the extent of tissue and organelle structural changes as a result of genetic mutations.

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Quantitative Approaches Cellular Structures Organelle Morphology Caenorhabditis Elegans Gene Function Genetic Mutations Software Non-subjective Assessment Synapses Muscles Mitochondria Nematode Morphology Qualitative Methods Phenotypic Differences Robust Methods Less Biased Assessment Model Organisms Disease-associated Mutations Slides For Imaging Agarose Pad
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