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JoVE Journal Cancer Research
Usando células-tronco pluripotentes induzidas pelo homem para a geração de células T específicas de antígeno tumoral
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Usando células-tronco pluripotentes induzidas pelo homem para a geração de células T específicas de antígeno tumoral

Article DOI: 10.3791/59997-v • 10:57 min • October 24th, 2019
October 24th, 2019 •
*1,2, *1,2, 1,2, 1,2, 1, 3, 1,2
1Surgery Branch, National Cancer Institute, NIH, 2Center for Cell-Based Therapy, National Cancer Institute, NIH, 3Laboratory of Immunology, Institute for Frontier Life and Medical Sciences, Kyoto University
* These authors contributed equally

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Este artigo descreve um método para gerar células-tronco pluripotentes induzidas por antígeno funcional do tumor derivadas de CD8αβ+ únicas células T positivas usando o sistema de cocultura OP9/DLL1.

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Pesquisa do câncer Edição 152 célula-tronco pluripotente célula-tronco pluripotente induzida imunologia transferência de células adotivas diferenciação de células T especificidade de antígeno tumoral
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