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JoVE Journal Genetics
En metode til at studere de Novo dannelse af kromatin domæner
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En metode til at studere de Novo dannelse af kromatin domæner

Article DOI: 10.3791/60039-v • 07:34 min • August 23rd, 2019
August 23rd, 2019 •
1,2,3, 1,2
1Howard Hughes Medical Institute, New York University School of Medicine, 2Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, 3Whitehead Institute for Biomedical Research

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Denne metode er designet til at følge dannelsen af PRC2-mediated kromatin domæner i cellelinjer, og metoden kan tilpasses til mange andre systemer.

Tags

Genetik PRC2 kromatin domæner H3K27me2 H3K27me3 Epigenetik nukleation spredning inducerbar/betinget redning.
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