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Journal / Genetics / Метод изучения де Ново Формирование хрометинов…
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JoVE Journal Genetics
Метод изучения де Ново Формирование хрометинов доменов
A Protocol to Evaluate and Quantify Retinal Pigmented Epithelium Pathologies in Mouse Models of Age-Related Macular Degeneration
Journal (Genetics)
A Protocol to Evaluate and Quantify Retinal Pigmented Epithelium Pathologies in Mouse Models of Age-Related Macular Degeneration
Genome-wide Determination of Mammalian Replication Timing by DNA Content Measurement
Journal (Genetics)
Genome-wide Determination of Mammalian Replication Timing by DNA Content Measurement
 
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Метод изучения де Ново Формирование хрометинов доменов

Article DOI: 10.3791/60039-v • 07:34 min • August 23rd, 2019
August 23rd, 2019 •
1,2,3, 1,2
1Howard Hughes Medical Institute, New York University School of Medicine, 2Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, 3Whitehead Institute for Biomedical Research

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Summary
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Этот метод предназначен для последующего формирования PRC2-опосредованных доменов хроматина в клеточных линиях, и метод может быть адаптирован ко многим другим системам.

Tags

Генетика Выпуск 150 PRC2 хроматин доменов H3K27me2 H3K27me3 эпигенетика нуклеация распространение индуцируемое / условное спасение.
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