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Immunology and Infection

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Indução meningocócica meningite sorogrupo C em camundongos via parto intracisternal
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Indução meningocócica meningite sorogrupo C em camundongos via parto intracisternal

Article DOI: 10.3791/60047-v • 10:03 min • November 5th, 2019
November 5th, 2019 •
1, 1, 1, 1, 1, 1, 2, 1, 1,3
1Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 2Department of Science and Technology, Sannio University, 3CEINGE – Advanced Biotechnology

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Aqui, descrevemos um método para induzir a meningite meningocócica através de uma via intracisternal de infecção em camundongos adultos. Apresentamos um protocolo passo a passo de infecção meningocócica desde a preparação do inóculo para a infecção intracisternal; registre então a sobrevivência animal e avalie as cargas bacterianas em tecidos do murine.

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Imunologia e Infecção Edição 153 Infecção Neisseria meningitidis,meningite meningocócica modelos de camundongos injeção intra-cisterna tecido cerebral cepa mutante isogênica.
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