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Journal / Immunology and Infection / Inducir meningitis meningocócica Serogrupo C en…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Inducir meningitis meningocócica Serogrupo C en ratones a través de parto intracisternal
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Inducir meningitis meningocócica Serogrupo C en ratones a través de parto intracisternal

Article DOI: 10.3791/60047-v • 10:03 min • November 5th, 2019
November 5th, 2019 •
1, 1, 1, 1, 1, 1, 2, 1, 1,3
1Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 2Department of Science and Technology, Sannio University, 3CEINGE – Advanced Biotechnology

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Aquí, describimos un método para inducir la meningitis meningocócica a través de una vía intracisternal de infección en ratones adultos. Presentamos un protocolo paso a paso de la infección meningocócica desde la preparación del inóculo hasta la infección intracisternal; luego registrar la supervivencia animal y evaluar las cargas bacterianas en los tejidos murinos.

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Inmunología e infección número 153 infección Neisseria meningitidis,meningitis meningocócica modelos de ratón inyección intracisternal tejido cerebral cepa mutante isogénica.
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