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Journal / Immunology and Infection / 葡萄糖-6-磷酸异构酶（G6PI）诱导RA小鼠中iNKT细胞的采用免疫治疗…
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Immunology and Infection

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JoVE Journal Immunology and Infection
葡萄糖-6-磷酸异构酶（G6PI）诱导RA小鼠中iNKT细胞的采用免疫治疗
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Pseudomonas aeruginosa Induced Lung Injury Model
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葡萄糖-6-磷酸异构酶（G6PI）诱导RA小鼠中iNKT细胞的采用免疫治疗

Article DOI: 10.3791/60048-v • 08:43 min • January 31st, 2020
January 31st, 2020 •
*1,2, *1,2, *1,2, *1,2, *1,2, *1,2, *1,2, *1,2, *1,2
1Medical School of Hebei University, 2Key Laboratory of Pathogenesis Mechanism and Control of Inflammatory-Autoimmune Diseases in Hebei Province
* These authors contributed equally

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该协议使用G6PI混合肽构建类风湿关节炎模型，更接近CD4+T细胞和细胞因子中的人类类风湿性关节炎模型。高纯度不变天然杀伤性T细胞（主要是iNKT2），具有特定的表型和功能，通过体内诱导和体外纯化获得，用于采用免疫治疗。

Tags

免疫学和感染，第155期，风湿性关节炎，采用免疫疗法，iNKT细胞，细胞因子，葡萄糖-6-磷酸异构酶（G6PI），体内成像系统（IVIS）
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