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Journal / Immunology and Infection / Imunoterapia adotiva de células iNKT em Isomerase …
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Immunology and Infection

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JoVE Journal Immunology and Infection
Imunoterapia adotiva de células iNKT em Isomerase Isomerase Induzida de Glicose-6-Fosfato (G6PI)-Induzido RaMice
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Imunoterapia adotiva de células iNKT em Isomerase Isomerase Induzida de Glicose-6-Fosfato (G6PI)-Induzido RaMice

Article DOI: 10.3791/60048-v • 08:43 min • January 31st, 2020
January 31st, 2020 •
*1,2, *1,2, *1,2, *1,2, *1,2, *1,2, *1,2, *1,2, *1,2
1Medical School of Hebei University, 2Key Laboratory of Pathogenesis Mechanism and Control of Inflammatory-Autoimmune Diseases in Hebei Province
* These authors contributed equally

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Este protocolo usa peptídeos mistos G6PI para construir modelos de artrite reumatoide que estão mais próximos do da artrite reumatoide humana em células CD4+ T e citocinas. Células T assassinas naturais invariantes de alta pureza (principalmente iNKT2) com fenótipos e funções específicas foram obtidas por indução in vivo e purificação in vitro para imunoterapia adotiva.

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Imunologia e Infecção Edição 155 artrite reumatoide imunoterapia adotiva células iNKT citocinas glicose-6-fosfato isomerase (G6PI) no sistema de imagem vivo (IVIS)
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