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Journal / Immunology and Infection / Antijenik Peptid ve Fc-III Mimetics (DCAF) Çift…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Antijenik Peptid ve Fc-III Mimetics (DCAF) Çift Fonksiyonlu Konjuge tarafından Hedefli Antikor Engelleme
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Antijenik Peptid ve Fc-III Mimetics (DCAF) Çift Fonksiyonlu Konjuge tarafından Hedefli Antikor Engelleme

Article DOI: 10.3791/60063-v • 09:39 min • September 17th, 2019
September 17th, 2019 •
*1,2, *3, 2, 2, 2, 3, 1,2
1Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, 2Mass Spectrometry Core Facility, School of Life Sciences, Westlake University, 3MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University
* These authors contributed equally

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Antijenik peptid ve Fc-III mimetik (DCAF) çift fonksiyonlu bir konjuge gelişimi zararlı antikorların ortadan kaldırılması için yeni bir yeniliktir. Burada, Dang virüsü enfeksiyonu sırasında antikorbağımlı geliştirme etkisini ortadan kaldırmak için seçici olarak 4G2 antikor engelleyebilir DCAF1 molekülünün sentezi için ayrıntılı bir protokol açıklar.

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Retraksiyon Sayı 151 DCAF hedefli tedavi antikor yerli kimyasal ligasyon katı faz peptid sentezi protein ekspresyonu ve saflaştırma ELISA
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