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Journal / Immunology and Infection / Mekanistisk indsigt i udviklingen af…
JoVE Journal
Immunology and Infection

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JoVE Journal Immunology and Infection
Mekanistisk indsigt i udviklingen af TNBS-medieret intestinal fibrose og evaluere de hæmmende virkninger af Rapamycin
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Mekanistisk indsigt i udviklingen af TNBS-medieret intestinal fibrose og evaluere de hæmmende virkninger af Rapamycin

Article DOI: 10.3791/60067-v • 10:21 min • September 12th, 2019
September 12th, 2019 •
1,2,3, 4, 4, 4, 1,2
1Department of Molecular and Cellular Physiology, Albany Medical College, 2The IBD Center, Division of Gastroenterology, Department of Medicine, Albany Medical College, 3Department of Geriatrics, School of Medicine and Health Science, University of North Dakota, 4Department of Neuroscience and Experimental Therapeutics, Albany Medical College

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I denne undersøgelse beskriver vi en detaljeret procedure for TNBS-medieret intestinal fibrose, som udviser sammenlignelig Patofysiologi til Crohns fibrose. Vi diskuterer også denne tilgang i lyset af Rapamycin faciliterede hæmmende virkninger på tarm fibrose.

Tags

Immunologi og infektion TNBS-medieret tarm fibrose Crohns sygdom inflammation Rapamycin autophagy hjemmehørende makrofag genekspression
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