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Kronisk salmonella infektion induceret tarm fibrose

Article DOI: 10.3791/60068-v • 08:40 min • September 22nd, 2019
September 22nd, 2019 •
1, 1, 1, 1
1The Biomedical Research Centre, University of British Columbia

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Denne protokol beskriver en musemodel af salmonella drevet tarm fibrose, der ligner de vigtigste patologiske kendetegn af Crohns sygdom, herunder transmural inflammation og fibrose. Denne metode kan bruges til at evaluere værts faktorer, der ændrer fibrotiske udfald ved hjælp af muterede mus, som vedligeholdes på en C57Bl/6 genetisk baggrund.

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Immunologi og infektion fibrose salmonella inflammatorisk tarmsygdom Crohns sygdom kronisk sygdom,
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