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Immunology and Infection

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JoVE Journal Immunology and Infection
Kronisk salmonella infektion inducerad intestinal fibros
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Kronisk salmonella infektion inducerad intestinal fibros

Article DOI: 10.3791/60068-v • 08:40 min • September 22nd, 2019
September 22nd, 2019 •
1, 1, 1, 1
1The Biomedical Research Centre, University of British Columbia

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Detta protokoll beskriver en musmodell av salmonella driven intestinal fibros som liknar viktiga patologiska kännetecken för Crohns sjukdom inklusive transmural inflammation och fibros. Denna metod kan användas för att utvärdera värd faktorer som förändrar fibrotiska resultat med muterade möss upprätthålls på en C57Bl/6 genetisk bakgrund.

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Immunologi och infektion fibros salmonella inflammatorisk tarmsjukdom Crohns sjukdom kronisk sjukdom mus
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