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Journal / Cancer Research / Fare Meme Epitel HC11 ve EpH4 Hücrelerinin…
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JoVE Journal Cancer Research
Fare Meme Epitel HC11 ve EpH4 Hücrelerinin Farklılaşması
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Fare Meme Epitel HC11 ve EpH4 Hücrelerinin Farklılaşması

Article DOI: 10.3791/60147-v • 09:32 min • February 27th, 2020
February 27th, 2020 •
*1,2, *1, *1,3, 1,4, 1, 1, 2, 1
1Department of Biomedical and Molecular Sciences and Department of Pathology and Molecular Medicine, Queen's University, Kingston, 2Department of Chemical and Physical Sciences, University of Toronto, Mississauga, 3Department of Laboratory Medicine, Brampton Civic Hospital Campus, William Osler Health System, 4Latner Thoracic Surgery Research Laboratories
* These authors contributed equally

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Biz iki meme epitel hatları, HC11 ve EpH4 farklılaşma indüksiyon teknikleri açıklayın. Her ikisi de süt proteinleri üretmek için fetal buzağı serumu, insülin ve prolaktin gerektirirken, EpH4 hücreleri üç boyutlu kültürde mammospheres içine tam olarak ayırt edebilirsiniz. Bu tamamlayıcı modeller farklılaşma ve neoplazi sinyal iletimi çalışmaları için yararlıdır.

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Kanser Araştırmaları Sayı 156 hücre farklılaşması meme epitel hücreleri prolaktin EHS matriks
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