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Modello porcinario dell'aneurisma aortico addominale a infrarosso
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Modello porcinario dell'aneurisma aortico addominale a infrarosso

Article DOI: 10.3791/60169-v • 11:13 min • November 21st, 2019
November 21st, 2019 •
1, 1, 1, 1, 1, 1, 1, 2, 3, *1, *1,4, *3
1Department of Surgery, University of Virginia School of Medicine, 2Department of Surgery, Ochsner Medical Center, 3Department of Surgery, University of Florida, 4The Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine
* These authors contributed equally

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Questo nuovo modello crea robusti aneurismi aortici infrarossi nei suini utilizzando una combinazione di angioplastica a palloncino, perfusione di elastasi/collagesi, applicazione di elastasi topica e somministrazione orali composto di ammisofino, che interferisce con il cross-linking di collagene.

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Medicina Numero 153 Malattia cardiovascolare aneurismi aortici citochine immunohistochimica macrofagi infiammazione
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