Waiting
Login processing...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Chemistry / 药物药代动力学和毒理学评估的肠道/肝脏微生理系统…
JoVE Journal
Chemistry

A subscription to JoVE is required to view this content.

JoVE Journal Chemistry
药物药代动力学和毒理学评估的肠道/肝脏微生理系统
Construction of Cyclic Cell-Penetrating Peptides for Enhanced Penetration of Biological Barriers
Journal (Chemistry)
Construction of Cyclic Cell-Penetrating Peptides for Enhanced Penetration of Biological Barriers
NMR-Based Activity Assays for Determining Compound Inhibition, IC50 Values, Artifactual Activity, and Whole-Cell Activity of Nucleoside Ribohydrolases
Journal (Chemistry)
NMR-Based Activity Assays for Determining Compound Inhibition, IC50 Values, Artifactual Activity, and Whole-Cell Activity of Nucleoside Ribohydrolases
 
Click here for the English version

药物药代动力学和毒理学评估的肠道/肝脏微生理系统

Article DOI: 10.3791/60184-v • 08:59 min • December 3rd, 2020
December 3rd, 2020 •
1, 4, 1, 1,2, 1, 1, 1, 3, 3, 1
1Brazilian Biosciences National Laboratory (LNBio), Brazilian Center for Research in Energy and Materials (CNPEM), 2Brazilian Synchrotron Light Laboratory (LNLS), Brazilian Center for Research in Energy and Materials (CNPEM), 3Grupo Boticário, 4Institute of Biology, University of Campinas

Summary
Automatic Translation

Please note that all translations are automatically generated.

Click here for the English version.

我们向对乙酰氨基酚（APAP）暴露了含有肠道和肝脏器官的微生理系统（MPS）。本文介绍了MPS中器官生产和APAP药代动力学和毒理学属性评估的方法。它还描述了验证结果所需的组织功能分析。

Tags

化学， 问题 166， 微生理系统， 对乙酰氨基酚， ADMETox， 有机体
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter