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JoVE Journal
Bioengineering

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在微流体进化加速器上生成跨癌症人群的异构药物梯度,用于实时观察
 
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在微流体进化加速器上生成跨癌症人群的异构药物梯度,用于实时观察

Article DOI: 10.3791/60185-v 10:24 min September 19th, 2019
September 19th, 2019

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Summary

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我们提出了一个微流体癌片模型,即"进化加速器"技术,它为在单细胞明确定义的环境条件下癌症动力学的长期实时定量研究提供了一个可控的平台水平。这项技术有望成为基础研究或临床前药物开发的体外模型。

Tags

生物工程,第151期,微加工,片上癌症,肿瘤微环境,化疗梯度,抗药性,细胞迁移
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