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Immunology and Infection

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JoVE Journal Immunology and Infection
Implantatie en monitoring door PET/CT van een Orthothematisch model van menselijk pleura mesothelioom in Athymic muizen
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Implantatie en monitoring door PET/CT van een Orthothematisch model van menselijk pleura mesothelioom in Athymic muizen

Article DOI: 10.3791/60272-v • 07:54 min • December 21st, 2019
December 21st, 2019 •
1, 1, 1, 2, 2
1MicroPET/SPECT/CT Imaging Laboratory, Centre for BioMedical Imaging (CIBM), Division of Nuclear Medicine and Molecular Imaging, University Hospitals and University of Geneva, 2Division of Thoracic and Endocrine Surgery, University Hospitals and University of Geneva

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Dit artikel beschrijft de generatie van een orthotopic muismodel van menselijke pleura mesothelioom door implantatie van H2052/484 mesothelioom cellen in de pleuraholte van immuungecompromitteerde athymische muizen. De longitudinale monitoring van de ontwikkeling van intrapleurale tumoren werd beoordeeld door niet-invasieve multimodale [18F] -2-Fluoro-2-deoxy-D-glucose positron emissie tomografie en computertomografie beeldvorming.

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Immunologie en infectie probleem 154 kanker pleura mesothelioom Orthotopic xenotransplantatie Athymic Mouse niet-invasieve beeldvorming PET/CT-beeldvorming
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