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Characterization of the Effects of Migrastatic Inhibitors on 3D Tumor Spheroid Invasion by High-resolution Confocal Microscopy

Article DOI: 10.3791/60273-v • 09:17 min • September 16th, 2019
September 16th, 2019 •
1, 2, 1
1School of Applied Sciences, University of Huddersfield, 2Laboratory of Radiotherapy and Experimental Radiation Oncology, Humbertus Wald Tumorzentrum, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf

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Summary
Automatic Translation

The effects of migrastatic inhibitors on glioma cancer cell migration in three-dimensional (3D) invasion assays using a histone deacetylase (HDAC) inhibitor are characterized by high-resolution confocal microscopy.

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Migrastatic Inhibitors 3D Tumor Spheroid Invasion High-resolution Confocal Microscopy Cancer Models Assessment Of Migrastatic Drugs Tumor Environment-relevant Setting Cytotoxic Drugs In Cancer Effect Of Radiation On Cancer Proliferation And Cell Migration Medium Removal Step Collagen Replacement Confocal Microscope Delicate Handling Of Spheroids U251 Culture Medium Trypsinize Cancer Cells Hemocytometer Cell Suspensions
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