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Intratekal levering av Antisens Oligonukleotider i Rat Central nervesystemet
 
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Intratekal levering av Antisens Oligonukleotider i Rat Central nervesystemet

Article doi: 10.3791/60274
October 29th, 2019

Summary October 29th, 2019

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Her beskriver vi en metode for å levere narkotika til rotte sentralnervesystemet ved å implanting et kateter inn i korsryggen intratekal plass i ryggraden. Vi fokuserer på levering av antisens oligonukleotider, men denne metoden er egnet for levering av andre terapeutiske modaliteter også.

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