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Journal / Immunology and Infection / Imaging Human immunologiske synapse
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Immunology and Infection

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Imaging Human immunologiske synapse
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Imaging Human immunologiske synapse

Article DOI: 10.3791/60312-v • 09:37 min • December 26th, 2019
December 26th, 2019 •
*1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 3, 1,2, *1,2
1Instituto de Investigaciones Biomédicas Alberto Sols, CSIC-Universidad Autónoma de Madrid, 2Departamento de Bioquímica, Instituto de Investigaciones Biomédicas Alberto Sols CSIC-UAM, Facultad de Medicina, Universidad Autónoma de Madrid, 3Unidad de Audiovisuales, Facultad de Medicina, Universidad Autónoma de Madrid
* These authors contributed equally

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Denne protokollen bilder både immunologiske synapse formasjon og den påfølgende polarisert sekretoriske trafikk mot immunologiske synapse. Cellular konjugater ble dannet mellom en superantigen-pulserende Raji celle (fungerer som en antigen-presentere celle) og en Jurkat klone (fungerer som en effektor hjelper T-lymfocytter).

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Immunologi og infeksjon T-lymfocytter antigen-presentere celler immunologiske synapse mikrotubulinettverket-organisering-senter polarisert trafikk multivesicular organer
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