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Journal / Cancer Research / Vergelijking van uitgezaaide Clear Cell Renal…
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Cancer Research
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Vergelijking van uitgezaaide Clear Cell Renal Cell Carcinoma Model opgericht in muisnier en op Kip Chorioallantoic Membraan
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Vergelijking van uitgezaaide Clear Cell Renal Cell Carcinoma Model opgericht in muisnier en op Kip Chorioallantoic Membraan

Article DOI: 10.3791/60314-v • 05:36 min • February 8th, 2020
February 8th, 2020 •
*1, *1, 2, 3, 4, 5, 6, 7, 1, 1,8
1Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, 2Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, 3Department of Bioengineering, Hanyang University, 4Department of Ecology and Evolutionary Biology, University of California, Los Angeles, 5Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, 6School of Life Sciences, Beijing Normal University, 7Department of Urology, West China Hospital, Sichuan University, 8Department of Urology, David Geffen School of Medicine, University of California, Los Angeles
* These authors contributed equally

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Uitgezaaid helder celnieraal celcarcinomis is een ziekte zonder een uitgebreid diermodel voor grondig preklinisch onderzoek. Dit protocol illustreert twee nieuwe diermodellen voor de ziekte: het orthotopicalisch geïmplanteerde muismodel en het kipchorioallantoïsche membraanmodel, die beide longmetastasen aantonen die lijken op klinische gevallen.

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Kankeronderzoek nummer 156 niercelcareloom metastase diermodel nierimplantatie CAM VHL-gendeletie intratumorale heterogeniteit
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