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Journal / Cancer Research / 使用二甲基苯甲酸酯和12-O-Tetradecanyl…
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Cancer Research

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JoVE Journal Cancer Research
使用二甲基苯甲酸酯和12-O-Tetradecanyl Phorbol-13-醋酸酯（DMBA-TPA）的化学诱导皮肤致癌模型
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使用二甲基苯甲酸酯和12-O-Tetradecanyl Phorbol-13-醋酸酯（DMBA-TPA）的化学诱导皮肤致癌模型

Article DOI: 10.3791/60445-v • 04:12 min • December 19th, 2019
December 19th, 2019 •
*1, *1, 1,2, 1,2, 1
1Faculty of Medicine and Health Technology, Tampere University and Tampere University Hospital, 2Department of Clinical Microbiology, Fimlab Laboratories
* These authors contributed equally

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Summary
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两阶段皮肤致癌是由两种局部应用的化学物质诱发的。诱变7，12-二甲基苯甲酸酯）导致表皮细胞突变，并持续应用一般生长刺激剂12-O-tetradecanoyl phorbol-13-醋酸酯加速皮肤皮球菌的形成。

Tags

癌症研究， 问题 154， 皮肤癌， 化学致癌物， 诱变， 运动， DMBA-TPA， 心电图， 血管生成， 炎症， 肿瘤， 增殖
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