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Biochemistry

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JoVE Journal Biochemistry
En integrert Raman spektroskopi og Mass massespektrometri Platform å studere single-Cell Drug opptak, metabolisme, og effekter
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En integrert Raman spektroskopi og Mass massespektrometri Platform å studere single-Cell Drug opptak, metabolisme, og effekter

Article DOI: 10.3791/60449-v • 07:37 min • January 9th, 2020
January 9th, 2020 •
1,2, 1,2, 1
1Biodynamics Research Center (BDR), RIKEN, 2Research Center, Misr International University

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Denne protokollen presenterer en integrert Raman spektroskopi-Mass massespektrometri (MS) plattform som er i stand til å oppnå enkelt celle oppløsning. Raman spektroskopi kan brukes til å studere cellulær respons på narkotika, mens MS kan brukes til målrettet og kvantitativ analyse av narkotika opptak og metabolisme.

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Biokjemi enkelt celle analyse Raman spektroskopi masse massespektrometri legemiddel oppdagelse Tamoxifen nanospray ionisering
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