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Journal / Medicine / Periadventitial Terapötik Uygulama ile Sıçan…
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JoVE Journal Medicine
Periadventitial Terapötik Uygulama ile Sıçan Karotis Arter Basınç Kontrollü Segmental Balon Yaralanması
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Periadventitial Terapötik Uygulama ile Sıçan Karotis Arter Basınç Kontrollü Segmental Balon Yaralanması

Article DOI: 10.3791/60473-v • 06:53 min • July 9th, 2020
July 9th, 2020 •
1,2,3,5, 1,2,3,4,5
1Department of Surgery, Division of Vascular Surgery, University of North Carolina at Chapel Hill, 2Center for Nanotechnology in Drug Delivery, University of North Carolina at Chapel Hill, 3Curriculum in Toxicology & Environmental Medicine, University of North Carolina at Chapel Hill, 4Department of Cell Biology & Physiology, University of North Carolina at Chapel Hill, 5McAllister Heart Institute, University of North Carolina at Chapel Hill

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Sıçan şahdamar balonu yaralanması, aterosklerotik damarlarda kan akışını geri kazanmak için yapılan klinik anjiyoplasti prosedürünü taklit eder. Bu model, arteriyel duvarı dağıtarak ve endotel hücrelerinin intimal tabakasını indirgeyerek arteriyel yaralanma yanıtını indükler, sonuçta yeniden şekillendirmeye ve intimal hiperplastik yanıta neden olur.

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Tıp Sayı 161 Sıçan Karotis Arter Balon Yaralanması Vasküler Yaralanma Restenoz Neointimal Hiperplazi Periadventiyal İlaç Doğumu Arteriyel Yaralanma Yanıtı Damar Tadilatı Kardiyovasküler Hastalık Periferik Arter Hastalığı Vasküler Düz Kas Hücresi Işık Tabakası Floresan Mikroskopi
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