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JoVE Journal Bioengineering
Design de um stent traqueal biocompatível de droga em camundongos com estenose laringotraquena
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Design de um stent traqueal biocompatível de droga em camundongos com estenose laringotraquena

Article DOI: 10.3791/60483-v • 08:26 min • January 21st, 2020
January 21st, 2020 •
1, 2, 2, 2, 2, 2, 2
1Department of General Surgery, University of California, San Francisco, 2Department of Otolaryngology Head and Neck Surgery, Johns Hopkins School of Medicine

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A estenose de laringotracura resulta da deposição patológica da cicatriz que estreita crìtica a via aérea do traqueal e falta terapias médicas eficazes. Usando um stent PLLA-PCL (70% poli-L-lactide e 30% policaprolactona) como um sistema local de entrega de drogas, terapias potenciais destinadas a diminuir a proliferação de cicatrizna traqueia podem ser estudadas.

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Bioengenharia Edição 155 stent de luta contra drogas PLLA-PCL rapamicina estenose laringotra estenose traqueal fibrose
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