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Journal / Bioengineering / Laringotracheal Stenozlu Farelerde Biyouyumlu…
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Bioengineering

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JoVE Journal Bioengineering
Laringotracheal Stenozlu Farelerde Biyouyumlu İlaç Eluting Trakeal Stent Tasarımı
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Laringotracheal Stenozlu Farelerde Biyouyumlu İlaç Eluting Trakeal Stent Tasarımı

Article DOI: 10.3791/60483-v • 08:26 min • January 21st, 2020
January 21st, 2020 •
1, 2, 2, 2, 2, 2, 2
1Department of General Surgery, University of California, San Francisco, 2Department of Otolaryngology Head and Neck Surgery, Johns Hopkins School of Medicine

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Laringotracheal stenoz, trakeal hava yolunu kritik derecede daraltan ve etkili tıbbi tedavilerden yoksun patolojik skar birikiminden kaynaklanır. PlLA-PCL (%70 poli-L-laktit ve %30 polikaprolakon) stent kullanılarak lokal ilaç dağıtım sistemi olarak, trakeada skar proliferünü azaltmaya yönelik potansiyel tedaviler incelenebilir.

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Biyomühendislik Sayı 155 ilaç eluting stent PLLA-PCL rapamisin laringorracheal stenoz trakeal darlık fibrozis
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