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JoVE Journal Bioengineering
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Um modelo de cultura de matriz-adipócito extracelular humano para estudar crosstalk metabólico de matriz e células

Article DOI: 10.3791/60486-v • 09:04 min • November 7th, 2019
November 7th, 2019 •
1, 1, 1,2, 5, 1,2, 1, 2,3,4, 1,6
1Department of Surgery, University of Michigan Medical School, 2Department of Pediatrics and Communicable Diseases, University of Michigan Medical School, 3Graduate Program in Immunology, University of Michigan Medical School, 4Graduate Program in Cellular and Molecular Biology, University of Michigan Medical School, 5Undergraduate Research Opportunity Program, University of Michigan, 6Department of Surgery, Ann Arbor Veterans Affairs Healthcare System

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Descrevemos um sistema de cultura in vitro de matriz extracelular em 3D que permite a dissecação dos papéis da matriz e dos adipócitos em contribuir para o fenótipo metabólico do tecido adiposo.

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Bioengenharia Edição 153 adipócito tecido adiposo matriz extracelular diabetes captação de glicose obesidade
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