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Journal / Cancer Research / Ultralyd-guidet Orthotopic implantation av murine …
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Cancer Research

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JoVE Journal Cancer Research
Ultralyd-guidet Orthotopic implantation av murine bukspyttkjertelen ductal Adenokarsinom
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Ultralyd-guidet Orthotopic implantation av murine bukspyttkjertelen ductal Adenokarsinom

Article DOI: 10.3791/60497-v • 06:21 min • November 19th, 2019
November 19th, 2019 •
1, 2,3, 2,3, 2,3, 1,4
1Department of Medicine, Perelman School of Medicine, University of Pennsylvania, 2Pancreatic Cancer Mouse Hospital, Perelman School of Medicine, University of Pennsylvania, 3Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, 4Parker Institute for Cancer Immunotherapy, Perelman School of Medicine, University of Pennsylvania

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Vi beskriver en protokoll for ultralyd veiledet implantation av murine-avledet bukspyttkjertel ductal adenokarsinom cellelinjer direkte inn i den innfødte tumor området. Denne tilnærmingen resulterte i bukspyttkjertelen svulster oppdages av ultralyd skanning innen 2-4 uker av injeksjon, og betydelig redusert andelen tumor celle seeding på bukhulen i forhold til kirurgisk orthotopic implantation.

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Kreftforskning bukspyttkjertelen ductal adenokarsinom ultralyd orthotopic prekliniske modell
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